The microdevice could detect the first signs of a heart attack or stroke

The new facilities of the University’s School of Biomedical Engineering will allow further development of engineering for the microdevice, which is based on an integrated microfluidic chip.

Dr. Ju is working with a team of PhD students to create computational simulations of highly sensitive fluid dynamics to better understand the impact of mechanical forces that could cause blood buildup and clots.

Yunduo biomedical engineering student Charles Zhao said: “In the near future, we plan to apply artificial intelligence to understand a person’s blood work in order to create a personalized blood profile of that person “.

Research assistant Laura Moldovan said it has historically been difficult to predict when a heart attack or stroke could occur: “They appear to occur at random, sometimes without any physical symptoms, but in fact there there are small physical changes that take place in the blood: the key to this device is to be able to sensitively control these microscopic changes. ”

The team’s recent work, the post-microfluidic method for three-dimensional modeling of platelet-leukocyte interactions, was recently published in the Royal Society of Chemistry.

Statement

The research was supported by the National Heart Foundation of Australia (APP1028564; APP1048574; APP2003904); Australian Research Council (ARC) Discovery Project (DP200101970); NSW Cardiovascular Capacity Building Program (Early-Mid Career Researcher Scholarship); Ramaciotti Foundation Health Investment Grant (2020HIG76); Sydney Nano Research Schemes.

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